Front-line therapy of APL: Randomized comparison of ATRA and intensified chemotherapy including high dose cytosine-arabinoside versus ATRA and anthracyclines — a prospective, multicentre, randomized clinical trial of the German Acute Myeloid Leukemia Cooperative Group

Lengfelder E, et al. APL 2017:CO027 Background The APL-2005 study was started as an Acute Myeloid Leukemia Cooperative Group (AMLCG) trial with the intention to be part of an acute promyelocytic leukemia (APL) intergroup study with the PETHEMA LPA99 protocol as a...

Reduction of hospitalization and transfusion support with first-line ATO in combination with ATRA compared to chemotherapy in combination with ATRA in patients with APL: Monocentric experience

Autore F, et al. APL 2017:PO029 Background All-trans retinoic acid (ATRA) in combination with anthracycline-based chemotherapy has obtained high response rates, but is associated with potential long-term sequelae in patients with acute promyelocytic leukemia (APL)....